Synthesis of New Schiff's Bases Derived from 4-Phthalimidyl Acetophenone

Authors

  • Rana Abid Ali Department of Chemistry, College of Science, University of Baghdad Jadiriya, Baghdad-Iraq.

Keywords:

Schiff's bases, amic acid, imide, biological activity

Abstract

Eight new Schiff's bases were prepared in three steps. The first step includes synthesis of phthalamic acid from the reaction between phthalic anhydride with p-amino acetophenone which in turn fused in the second step to form the corresponding phthalimide. The third step involved condensation of the prepared phthalimide with different primary aromatic amines to form new Schiff's bases. These compounds were characterized by FT-IR, 1H-NMR and 13C-NMR spectroscopy. Most of the synthesized compounds have been screened for their antimicrobial activities by using agar cup plate method against two types of bacteria .The results showed that the new Schiff's bases exhibit good to moderate antibacterial activity. 

Published

2018-07-23

Issue

Section

Articles

How to Cite

(1)
Synthesis of New Schiff’s Bases Derived from 4-Phthalimidyl Acetophenone. ANJS 2018, 14 (3), 1-8.

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