Eco-Friendly Synthesis of Zinc Oxide: Green Chemistry Approaches and Innovations

Authors

  • Ayaa Kamal Department of Chemistry, College of Science, Al-Nahrain University, Baghdad, Iraq
  • Atheel H. Alwash Department of Chemistry, College of Science, Al-Nahrain University, Baghdad, Iraq
  • Emad Al-Sarraj Department of Chemistry / College of Sciences / Al-Nahrain University / IRAQ
  • Fatemeh Gholami Department of Mathematics, Physics and Technology, Faculty of Education, University of West Bohemia, Czech Republic
  • Noor Thiab Kangan Institute, Brodmeadows Campus, Victoria, Australia

DOI:

https://doi.org/10.22401/

Keywords:

Green Chemistry , Capping agent , Zinc oxide , Photocatalytic reaction

Abstract

Techniques of green production of zinc oxide nanoparticles, also called ZnO-NPs utilizing extracts of plants have drawn study interest in sustainable innovation due to its low cost, ease of use, and benefits for the natural world. This review presents a sustainable method for synthesizing zinc oxide nanoparticles, also known as ZnO-NP from plant extracts, and the features of zinc oxide nanoparticles are examined. These physical features attest to zinc oxide form, structure, crystal formation, and proportions. The dimensions form and dimensions significantly influence the zinc oxide nanoparticle's interface reactivity. A further benefit of capping compounds as stabilizing agents that limit nanoparticle growth, and avert the accumulation and disintegration in colloid synthesizing, is presented in the article review. The capping ligands maintain the connection between nanoparticles and their formation medium. Ultimately, zinc oxide has become one of the most favored options for the use of sunlight because of its spectral properties. The mechanism and its application in different fields have been summarized.

References

[1] Zhang, F.; Chen, X.; Wu, F.; and Ji,Y.; “High adsorption capability and selectivity of ZnO nanoparticles for dye removal”. Colloids Surf., A., 509:474–483 ,2016.

[ 2] Kamarudin, N. S.; Jusoh, R.; Setiabudi, H. D.; Sukor, N. F.; & Shariffuddin, J. H.; “Potential nanomaterials application in wastewater treatment: Physical, chemical and biological approaches”. Mater. Today Proc., 42:107-114, 2021.

[3 ] Yaqoob, A.A.; Parveen, T.; Umar, K. ; and Mohamad Ibrahim, M.N.; “Role of nanomaterials in the treatment of wastewater: A review”. Water., 12(2):495, 2020.

[4] Joga, S. and Koyyala, V.P.B. ; “Nanotechnology in Oncology”. Indian J. Med. Paediatr. Oncol. 42(01):93-95, 2021.

[5] Salam, H. A.; Rajiv, P.; Kamaraj, M.; Jagadeeswaran, P.; Gunalan, S. and Sivaraj, R.; “Plants: green route for nanoparticle synthesis”. Int. Res. J. Biol Sci., 1(5):85-90, 2012.

[6] Sidhu, A.K.; Verma, N. and Kaushal, P.; “Role of biogenic capping agents in the synthesis of metallic nanoparticles and evaluation of their therapeutic potential”. Front. nanotechnol, 3.801620, 2022.

[7] Ibrahim, T.A.; Salman, T.A. and Abbas, S.A.R. ; “Biosynthesis of zinc oxide nanoparticles using orange peels extract for biological applications”. Plant Arch., 21(1):329-332, 2021.

[8 ]Negrescu, A.M. ; Killian, M.S.; Raghu, S.N.V. ;Schmuki, P.; Mazare, A. and Cimpean A. ; “Metal Oxide Nanoparticles :Review of Synthesis”. J. Funct. Biomater.,13(4):274, 2022.

[ 9]Vijayaram, S.; Razafindralambo, H.; Sun, Y. Z.; Vasantharaj, S.; Ghafarifarsani, H.; Hoseinifar, S. H. and Raeeszadeh, M. ;“Applications of green synthesized metal nanoparticles—a review”. Biol. Trace Elem. Res., 202(1): 360-386, 2024.

[ 10] Battez, AH; González. R; Viesca, JL.; Fernández, JE.; Fernández, JD.; Machado, A.; Chou, R. and Riba J.; “CuO, ZrO2 and ZnO nanoparticles as antiwear additive in oil lubricants”. WEAR., 265(3–4):422–428, 2008.

[ 11 ] Ramesh, M.; Janani, R.; Deepa, C. and Rajeshkumar, L. ; “Nanotechnology-enabled biosensors: A review of fundamentals design principles: materials, and applications”. Biosens. J., 13(1):40, 2022.

[12 ] Hannachi, E.; Sayyed, M.I.; Slimani, Y.;Almessiere, M.A.; Baykal, A. and Elsafi, M. ;“Experimental study on the radiation protecting ability of composites containing barium titanate and nanospinel ferrite”. Radiat. Phys. Chem., 212:111126, 2023.

[13 ] Murhekar, M.V.; Bhatnagar, T.; Thangaraj, J.W.V.; Saravanakumar, V.; Kumar, M.S.; Selvaraju, S.; Rade, K.; Kumar, C.G.; Sabarinathan, R.; Turuk, A. and Asthana, S. ;“SARS-CoV-2 seroprevalence among the general population and healthcare workers in India, December 2020–January 2021”. Int J Infect Dis, 108:145-155, 2021.

[14 ] Hano, C. and Abbasi, B.; “ H.Plant-based green synthesis of nanoparticles: Production”. characterization and applications’’ Biomol.,12(1):31, 2021.

[15 ]Esa, Y. A. M. and Sapawe, N.A ;“short review on zinc metal nanoparticles synthesize by green chemistry via natural plant extracts”. Mater.Today Proc., 31:386-393, 2020.

[ 16] Awwad, A.M.; Amer, M.W.; Salem, N.M. and Abdeen, A.O.; “Green synthesis of zinc oxide nanoparticles (ZnO-NPs) using Ailanthus altissima fruit extracts and antibacterial activity”. .Chem. Int, 6(3):151-159, 2020.

[17 ] Luque, P.A.; Soto-Robles, C.A.; Nava, O.; Gomez-Gutierrez, C.M. ; Castro-Beltran, A.; Garrafa-Galvez, H.E. and Vilchis-Nestor, A.R.;“ Olivas, “A Green synthesis of zinc oxide nanoparticles using Citrus sinensis extract”. J. Mater. Sci.: Mater. Electron., 29:9764-9770, 2018.

[ 18] Nava, O. J.; “Fruit peel extract mediated green synthesis of zinc oxide nanoparticles”. J. Mol. Struct., 1147:1-6, 2017.

[19 ] Alwash, A .;“ The green synthesize of zinc oxide catalyst using pomegranate peels extract for the photocatalytic degradation of methylene blue dye”. Baghdad Sci. J., 17(3):0787-0787, 2020,

[20 ] Thi, T.U.D.; Nguyen, T.T.; Thi, Y.D.; Thi, K.H.T.; Phan, B.T. and Pham, K.N. ;“Green synthesis of ZnO nanoparticles using orange fruit peel extract for antibacterial activities”. RSC Adv., 10(40):23899-23907, 2020.

[21 ] Alnehia, A.;Al-Odayni, A.B.; Al-Sharabi, A.; Al-Hammadi, A.H. and Saeed, W.S.;“ Pomegranate peel extract-mediated green synthesis of ZnO-NPs: Extract concentration-dependent structure, optical, and antibacterial activity”. J. Chem., 1 (2022): 9647793, 2022

[22 ] Jayaprakash, N.; Suresh, R.; Rajalakshmi, S.; Raja, S.; Sundaravadivel, E.; Gayathri, M. and Sridharan,M.;“One stepsynthesis,Characterisation, photocatalytic and bio-medical applications of ZnO nanoplates”. Mater. Technol., 35(2):112-124, 2020.

[23 ] Ibrahim, T.A.;Salman, T.A. ; Abbas, S.A.R. ;“Biosynthesis of zinc oxide nanoparticles using orange peels extract for biological applications”. Plant Arch., 21(1): 329-332, 2021

[24 ] Mohammadi, F.M. and Ghasemi, N.;“Influence of temperature and concentration on biosynthesis and characterization of zinc oxide nanoparticles using cherry extract”. J. Nanostructure Chem., 8:93-102, 2018.

[25 ] Zhou, X.Q. ; Hayat, Z. ; Zhang, D.D. ; Li, M.Y. ; Hu, S. ; Wu, Q. ; Cao, Y.F. and Yuan, Y. ; “Zinc oxide nanoparticles: synthesis, characterization, modification, and applications in food and agriculture”. Processes, 11 (4): 1193, 2023.

[26 ] Phan CM. and Nyungen, HM.;“Role of capping agent in wet synthesis of nanoparticles”. J. Phys. Chem. A, 121(17):3213-3219, 2017.

[27 ] Chugh, D.; Viswamalya, V.S. ; Das, B.;“Green synthesis of silver nanoparticles with algae and the importance of capping agents in the process”. J. Genet. Eng. Biotechnol., 19(1):126, 2021.

[28 ] Javed, R.; Zia, M.; Naz, S.; Aisida, S.O.;Ain, N.U. and Ao, Q.;“ Role of capping agents in the application of nanoparticles in biomedicine and environmental remediation: recent trends and future prospects’’. J. Nanobiotechnology, 18:1-15 , 2020 .

[29 ] Dumanli, F. T. S.;“ Effect of Capping Agents on the Nanoscale Metal Borate Synthesis”. In Boron, Boron Compounds and Boron-Based Materials and Structures,Intech Open , 2023.

[30 ] Dhaka,A.; Mali, S.C.; Sharma, S. and Trivedi, R.A ;“review on biological synthesis of silver nanoparticles and their potential applications ”. Results Chem.,101108 , 2023.

[31 ] Wang, Z.L.; Kong, X.Y.; Ding, Y.; Gao, P.;Hughes, W.L.; Yang, R. and Zhang, Y. ;“Semiconducting and piezoelectric oxide nanostructures induced by polar surfaces”. Adv. Funct. Mater., 14(10):943-956, 2004 .

[32 ] Farag Singab, M. ; and El-Dafrawy, S. and Hassan, S. ; “ZnO and C/ZnO Catalysts Synthesized via Plant Mediated Extracts for Photodegradation of Crystal Violet and Methyl Orange Dyes”. J. Inorg. Organomet. Polym. Mater., 34(09):1-14,2023.

[ 33]Farag, M.; El-Dafrawy, S.M. and Hassan, S.M. ;“ZnO and C/ZnO catalysts synthesized via plant mediated extracts for photodegradation of crystal violet and methyl orange dyes’’. J. Inorg. Organomet. Polym. Mater. , 34(3): 930-943., 2023.

[34 ] La, M. ; Sharma, P. ; Ram, C. ; “Optical, structural properties and photocatalytic potential of Nd-ZnO nanoparticles synthesized by hydrothermal method”. Results Opt., 10 : 100371, 2023.

[35 ] Roy, N. and Chakraborty, S.; “ZnO as photocatalyst: An approach to waste water treatment” Mater .Today Proc., 46 : 6399-6403, 2021.

[36 ] Alwash, A. ; Ibrahim, M.F. ; Mohammed, S. ;”Effect of Banana Peels Extract Ratio on The Sustainable Eco-Friendly Synthesis of Zinc Oxide Nanoparticles”. Al-Nahrain J. Eng. Sci., 26(4):297-303.

[ 37] Darvishi, D.; Kahrizi, D. and Arkan, E. ;“Comparison of differ-ent properties of zinc oxide nanoparticles synthesized by the green(using Juglans regia L. leaf extract) and chemical methods”. J. Mol. Liq., 286:110831. 2019.

[38 ]Bayrami, A.; Alioghli, S.; Pouran, S. R.; Habibi-Yangjeh, A.; Khataee, A. and Ramesh, S. A ;“facile ultrasonic-aided biosynthesis of ZnO nanoparticles using Vaccinium arctostaphylos L. leaf extract and its antidiabetic, antibacterial, and oxidative activity evaluation”. Ultrason. Sonochem., 55:57-66, 2019.

[39 ] Erten-Ela,S.;“Photovoltaic Performance of ZnO Nanorod and ZnO: CdO Nanocomposite Layers in Dye‐Sensitized Solar Cells (DSSCs)”. Int. J. Photoenergy 1:436831, 2013.

[ 40] Kakarndee, S. and Nanan, S.; “SDS capped and PVA capped ZnO nanostructures with high photocatalytic performance toward photodegradation of reactive red (RR141) azo dye”. J. Environ. Chem. Eng., 6(1):74-94, 2018.

[ 41] Wang, J.; Li, X.; Teng, C.; Xia, Y.; Xu, J.; Xie, D. and Komarneni, S. ;“Ligand-directed rapid formation of ultralong ZnO nanowires by oriented attachment for UV photodetectors”. J. Mater. Chem. C, 4(24): 5755-5765, 2016.

[ 42] Jianzhong, M. ; Liu, J. ; Bao, Y. ; Zhu, Z. ; & Liu, H. ;“Morphology‐photocatalytic properties‐growth mechanism for ZnO nanostructures via microwave‐assisted hydrothermal synthesis’’. Cryst. Res. Technol., 48(4): 251-260, 2013.

[43 ] Sreevalsa, V. G.; Jeeju, P. P.; Augustine, M. S.; Anilkumar, K. M. and Jayalekshmi, S.;“ L-Histidine-modified biocompatible zinc oxide nanocrystals’’. J. Exp. Nanosci., 8(7-8), 937-946, 2013.

[44 ] Tarlani, A.; Fallah, M.; Lotfi, B.; Khazraei, A.; Golsanamlou, S.; Muzart, J. and Mirza-Aghayan, M. ;“ New ZnO nanostructures as non-enzymatic glucose biosensors’’. Biosens. Bioelectron., 67:601-607,2015.

[ 45] Morsbach, E.; Spéder, J.; Arenz, M.; Brauns, E.; Lang, W.; Kunz, S. ; and Bäumer, M. ; “Stabilizing catalytically active nanoparticles by ligand linking: toward three-dimensional networks with high catalytic surface area’’. Langmuir, 30(19):5564_5573, 2014.

[46 ] Duo, S.; Zhong, R.; Liu, Z.; Wang, J.; Liu, T.;Huang, C. and Wu, H. ;“ One-step hydrothermal synthesis of ZnO microflowers and their composition-/hollow nanorod-dependent wettability and photocatalytic property’’. J. Phys. Chem. Solids, 120:2033., 2018.

[47 ] Parra, M. R. and Haque, F. Z. ;“Structural and optical properties of poly-vinylpyrrolidone modified ZnO nanorods synthesized through simple hydrothermal process’’. Optik, 125(17):4629-4632, 2014.

[ 48 ] Chen, Y. Y.; Kuo, C. C.; Chen, B. Y.; Chiu, P. C. and Tsai, P. C. ;“Multifunctional polyacrylonitrile‐Z n O/A g electrospun nanofiber membranes with various Z n O morphologies for photocatalytic, UV‐shielding, and antibacterial applications’’. J. Polym. Sci., Part B: Polym. Phys. , 53(4):262-269., 2015.

[ 49] Anand, K.; Varghese, S. and Krishnamoorthy, A. ;“Role of surfactants on the stability of nano-zinc oxide dispersions’’. Part. Sci. Technol, 35: 67-70., 2017.

[50 ]Alizadeh, R.; “Chlorophenol’s ultra-trace analysis in environmental samples by chitosan–zinc oxide nanorod composite as a novel coating for solid phase micro-extraction combined with high performance liquid chromatography’’. Talanta, 146: 831-838., 2016.

[51 ] Vidhya, K.; Saravanan, M.; Bhoopathi, G.; Devarajan, V. P. and Subanya, S. ;“Structural and optical characterization of pure and starch-capped ZnO quantum dots and their photocatalytic activity’’. Appl. Nanosci., 5, 235-243., 2015.

[ 52] Nanomed, G. J. ;“Use of Honey in Stabilization of ZnO Nanoparticles Synthesized via Hydrothermal Route and Assessment of their Antibacterial Activity and Cytotoxicity’’. Glob J Nano., 2:2: 555585. ,2017.

[53 ] Golmohammadi, M.; Honarmand, M. and Ghanbari, S. ; “A green approach to synthesis of ZnO nanoparticles using jujube fruit extract and their application in photocatalytic degradation of organic dyes’’. Spectrochim. Acta - A: Mol. Biomol. Spectrosc., 229:117961., 2020.

[54 ] Moghaddas, S. M. T. H.; Elahi, B. and Javanbakht, V.;“ Biosynthesis of pure zinc oxide nanoparticles using Quince seed mucilage for photocatalytic dye degradation’’. J. Alloys Compd. 821:153519, 2020.

[ 55] Abdullah, F. H.; Bakar, N. A. and Bakar, M. A. “Low temperature biosynthesis of crystalline zinc oxide nanoparticles from Musa acuminata peel extract for visible-light degradation of methylene blue’’. Optik,206:164279, 2020.

[56 ] Sharma, S.; Kumar, K.; Thakur, N.; Chauhan, S., and Chauhan, M. S. ;“The effect of shape and size of ZnO nanoparticles on their antimicrobial and photocatalytic activities: a green approach’’. Bull. Mater. Sci., 43: 1-10., 2020.

[57 ] Abdol Aziz, R.A.; Abd Karim, S.F.; Ibrahim, U.K. and Sanuddin, N. ;“Precursor concentration effect on physicochemical properties of zinc oxide nanoparticle synthesized with banana peel extract’’. Key Eng. Mater., 797:262-270, 2019.

[ 58] Ramesh, P.; Saravanan, K.; Manogar, P.; Johnson, J.; Vinoth, E. and Mayakannan, M.;“Green synthesis and characterization of biocompatible zinc oxide nanoparticles and evaluation of its antibacterial potential”. Sens. Bio-Sens. Res.,31:100399, 2021

[59 ]Rasli, N.I., Basri, H. and Harun, Z. “Zinc oxide from aloe vera extract: two-level factorial screening of biosynthesis parameters”. Heliyon, 6(1):1,2020

[ 60] Mfon, R.E.; Hall, S.R. and Sarua, A.;“Effect of ocimum gratissimum plant leaf extract concentration and annealing temperature on the structure and optical properties of synthesized zinc oxide nanoparticles”. J. Sci. Math. Technol. Educ., 7(1):1-13,2020

[ 61] Iménez-Rosado, M.; Gomez-Zavaglia, A.; Guerrero, A. and Romero, A.; “Green synthesis of ZnO nanoparticles using polyphenol extracts from pepper waste (Capsicum annuum)’’. J. Clean. Prod., 350:131541, 2022.

[62 ] Alharbi, F.N.; Abaker, Z.M.; Makawi, S.Z.A. ;“Phy tochemical Substances—Mediated Synthesis of Zinc Oxide Nanoparticles (ZnO NPS)’’. Inorganics , 11:328, 2023.

[ 63] Singhal, U.; Pendurthi, R. and Khanuja, M. ;

“Prunus: A natural source for synthesis of zinc oxide nanoparticles towards photocatalytic and antibacterial”. Mater. Today: Proc. ,1;28:261-5,2020

[ 64]Pillai, AM.; Sivasankarapillai, VS.; Rahdar, A.; Joseph, J.; Sadeghfar, F.; Rajesh, K., Kyzas, GZ. ;“Green synthesis and characterization of zinc oxide nanoparticles with antibacterial and antifungal activity’’. J. Mol. Struct. ,5.1211:128107, 2020

[65 ] Viswanathan, V.; Arokiadhas, I.; Rajagopalan, T.; Marimuthu, G.; Naiyf, S. A.; Shine K.; Jamal, M. K.; Mohammed, N. A. and Baskaralingam, V.; “Synthesis of ZnO nanoparticles using insulin-rich leaf extract: Anti-diabetic, antibiofilm and antioxidant properties’’. J. Photochem. Photobiol. B: Biol., 197:111541, 2019.

[66 ] Velsankar, K.; Sudhahar, S.; Parvathy, G. and Kaliammal, R; “Effect of cytotoxicity and aAntibacterial activity of biosynthesis of ZnO hexagonal shaped nanoparticles by Echinochloa frumentacea grains extract as a reducing agent’’. Mater. Chem. Phys.,239:121976,2020

[67 ] Rajashekara, S.; Shrivastava, A.; Sumhitha, S. and Kumari S.; “Biomedical Applications of Biogenic Zinc Oxide Nanoparticles Manufactured from Leaf Extracts of Calotropis gigantea (L.) Dryand’’. Bionanoscience., 10:65471, 2020.

[68 ] Jahan, N.; Rasheed, K.; Rahman, KU. ; “Green inspired synthesis of zinc oxide nanoparticles using Silybum marianum (milk thistle) extract and evaluation of their potential pesticidal and phytopathogens activities’’. Peer J., 11:15743, 2023.

[69 ] Javed, Z.; Tripathi, GD.; Mishra, M.; Gattupalli, M. and Dashora, K. ; “Cow dung extract mediated green synthesis of zinc oxide nanoparticles for agricultural applications’’. Sci. Rep. 27;12(1):20371,2022

[ 70] Suresh, D.; Shobharani, R.M.; Nethravathi, P.C.; Kumar, M.P.; Nagabhushana, H. and Sharma, S.C. ;“Artocarpus gomezianus aided green synthesis of ZnO nanoparticles: Luminescence, photocatalytic and antioxidant properties’’. Spectrochim. Acta - A: Mol. Biomol. Spectrosc., 141:128-134, 2015.

[ 71] Bala, N.; Saha, S.; Chakraborty, M.; Maiti, M.; Das, S.; Basu, R. and Nandy, P. ; “ Green synthesis of zinc oxide nanoparticles using Hibiscus subdariffa leaf extract: effect of temperature on synthesis, anti-bacterial activity and anti-diabetic activity’’. RSC Adv. ,5(7):4993-5003,2015

[ 72] Noman, M.T.; Amor, N. and Petru, M.; “Synthesis and applications of ZnO nanostructures (ZONSs): A review’’. Crit. Rev. Solid State Mater. Sci., 47(2):99-141, 2022.

[ 73] Osuntokun, J.; Onwudiwe, D.C. and Ebenso, E.E.;“Green synthesis of ZnO nanoparticles using aqueous Brassica oleracea L. var. italica and the photocatalytic activity’’. Green Chem. Lett. Rev. , 12(4): 444-457, 2019.

[74 ] Haque, M.J.; Bellah, M.M.; Hassan, M.R. and Rahman, S. ;“Synthesis of ZnO nanoparticles by two different method & comparison of their structural, antibacterial, photocatalytic and optical properties’’. Nano Express, 1(1): 010007,2020

[ 75] Mydeen, S.S.; Kumar, R.R.; Kottaisamy, M. and Vasantha, V.S. ; “Biosynthesis of ZnO nanoparticles through extract from Prosopis juliflora plant leaf: Antibacterial activities and a new approach by rust-induced photocatalysis’’. J. Saudi Chem. Soc., 24(5):393-406, 2020.

[ 76]Chemingui, H.; Missaoui, T.; Mzali, J.C.; Yildiz, T.; Konyar, M.; Smiri, M.; Saidi, N.; Hafiane, A. and Yatmaz, H.C.;“ Facile green synthesis of zinc oxide nanoparticles (ZnO NPs): Antibacterial and photocatalytic activities’’. Mater. Res. Express, 6(10): 1050b4, 2019.

[77 ] Matinise, N.; Fuku, X.G.; Kaviyarasu, K.; Mayedwa, N. and Maaza, M.; “ZnO nanoparticles via Moringa oleifera green synthesis: physical properties & mechanism of formation’’. Appl. Surf. Sci., 406:339–347,2017.

Downloads

Published

2025-03-15

Issue

Section

Articles

How to Cite

(1)
Eco-Friendly Synthesis of Zinc Oxide: Green Chemistry Approaches and Innovations. ANJS 2025, 28 (1), 40-55. https://doi.org/10.22401/.

Most read articles by the same author(s)