Synthesis and Characterization of Some New 1,2,3-Triazole, Pyrazolin-5-one and thiazolidinone Derivatives

Authors

  • Huda Ahmed Hassan Department of Chemistry, College of Education Ibn-Al-Haithem, University of Baghdad, Baghdad-Iraq.

Keywords:

1,2,3- Triazole, pyrazolin-5-one, Schiff bases, thiazolidinone

Abstract

Five membered heterocyclics derivatives were synthesized in this work by three routes. The first route includes the synthesis of N-benzoic acid 1,2,3,-triazole derivatives (3),(4) by diazotation of methyl-2-amino benzoate and treating the resulted salt (1) with sodium azide and ethyl acetoacetate or acetyl acetone, respectively. In the second route, derivatives of pyrazole (8) pyrazolin-5-one (9), (10) were prepared by the reaction of the salt (1) with some active methylene compounds to give the corresponding hydrazones derivatives (5-7) which then they were treated with hydrazine hydrate. The third route afforded the synthesis of three derivatives (12), (15a), (15b) of thiazolidinone by two different methods. AII compounds were confirmed by their melting points, FTIR, U.V-vis spectra and 1 H-NMR spectra for some of them.

 

Published

2013-03-01

Issue

Section

Articles

How to Cite

(1)
Synthesis and Characterization of Some New 1,2,3-Triazole, Pyrazolin-5-One and Thiazolidinone Derivatives. ANJS 2013, 16 (1), 53-59.