Synthesis of 2-Mercaptobenzimidazole and Some of its Derivatives

Authors

  • Mohammed R Ahamed Department of Chemistry, College of Science, University of Baghdad, Baghdad-Iraq.
  • Shetha F Narren Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad-Iraq
  • Amal S Sadiq Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad-Iraq

Keywords:

2-Mercaptobenzimidazole, alkylation, oxidation

Abstract

The present work involved three steps: First step include synthesis of 2-mercaptobenzimidazole from reaction of o-phenylenediamine with carbon disulfide, in the second step: Alkylation of the 2-mercaptobenzimidazole with different alkyl halides or aryl to obtain thioether compounds. Third step: include oxidation of 2-mercaptobenzimidazole to disulfide, while oxidation of thioether compounds gave sulfone compounds by using hydrogen peroxide as oxidizing agent for (1-2h) with stirring at room temperature. The 2-mercaptobenzimidazole was prepared in autoclave. Structure confirmation of all prepared compounds were proved using FT-IR and elemental analysis (C.H.N.S) besides melting points.



Published

2013-06-01

Issue

Section

Articles

How to Cite

(1)
Synthesis of 2-Mercaptobenzimidazole and Some of Its Derivatives. ANJS 2013, 16 (2), 77-83.