The Effect of Acute and Chronic Noise Stress Exposure on some Physiological and Immunological Parameters in Male and Female Adult Mice
DOI:
https://doi.org/10.22401/chej3z39Keywords:
Chronic Noise , Stress , IgG, IgMAbstract
Noise, the most commonly encountered stressor in our daily lives, affects the body in different ways depending on its frequency, intensity, and duration. Thus, this study aimed to demonstrate the effect of noise stress exposure in different durations on the immunological status of female and male adult mice. Sixty female and male adult mice (Balb / C) were used in this. Fifty mice were exposed to noise stress at 90 degrees for four hours per day, and 10 mice (5 males and 5 females) were left without exposure to stress which was used as a control group. Exposure stress mice were divided into five groups (n = 10, 5 males and 5 females); Group1 was exposed to noise stress for only 1 day, Group2 for 8 days, Group3 for 14 days, Group4 for 21 days, and Group5 for 30 days. The blood sample was collected and used for immunoglobulins, glucocorticoids and WBCs indices tests. Results showed that there was a highly significant increase in glucocorticoids for all periods after noise exposure. WBC count, the level of IgG and IgM were highly significant in mice that were exposed to noise stress during 1, 8, 14, and 21 days, while there was no significant difference in the 28-days stress group compared to control. In conclusion, the levels of immunoglobulins levels after 28 day of noise stress exposure could completely differ from the short-term exposure.
References
Salehpour F.; Mahmoudi J.; Eyvazzadeh N.; "Effects of acute and chronic noise stress on depressive-and anxiety-like behaviors in mice". JECNS, 5(1): 1-6, 2018.
Barzegar M.; Sajjadi F. S.; Talaei S. A.; Hamidi G.; Salami M.; "Prenatal exposure to noise stress: anxiety, impaired spatial memory, and deteriorated hippocampal plasticity in postnatal life". Hippocampus, 25(2): 187-196, 2015.
Khanam S.; "Impact of stress on physiology of endocrine system and on immune system: A Review”. Inter. J. Diabetes Endocrinol., 2(3): 40-42, 2017.
Vitlic A.; Lord J.M.; Phillips A.C.S.; "Ageing and their influence on functional, cellular and molecular aspects of the immune system". Age, 36(3): 1169-1185, 2014.
Khan F.A.; "Biotechnology in Medical Sciences". CRC Press: 328-341, 2014.
Ball, G.F.; "Vitamins: their role in the human body”. John Wiley & Sons, 2008.
Stavnezer J.; Guikema J.E.; Schrader C.E.; "Mechanism and regulation of class switch recombination". Annu. Rev. Immunol., 26(261), 2008.
Janeway J.C.A.; Travers P.; Walport M.; Shlomchik M.J.; "The distribution and functions of immunoglobulin isotypes". In Immunobiology: The Immune System in Health and Disease. 5th edition. Garland Science., 2001.
Hitti, M.; Chang L.; "Chronic fatigue syndrome linked to hormone". J. Clin. Endocrinol. Metab., 22: 326-30, 2008.
Podsevatkin V.G.; Kiriukhina S.V.; Podsevatkin D.V.; Podsevatkina S.V.; Blinov D.S.; "Dynamics of the behavioral response and cortisole level caused by the combined action of mexidole, diazepam, thymogen, and hyperbaric oxygenation in mice under immobilization stress conditions". Eksp. Klin. Farmakol., 71(1): 22-25, 2008.
Zhang J.; "Basic neural units of the brain: neurons, synapses and action potential". arXiv preprint arXiv:1906.01703, 2019.
Zavala J.K.; Fernandez A.A.; Gosselink K.L.; "Female responses to acute and repeated restraint stress differ from those in males". Physiol. behav., 104(2): 215- 221, 2011.
Iwasaki-Sekino, A.; Mano-Otagiri, A.; Ohata, H.; Yamauchi, N.; Shibasaki, T.; "Gender differences in corticotropin and corticosterone secretion and corticotropinreleasing factor mRNA expression in the paraventricular nucleus of the hypothalamus and the central nucleus of the amygdala in response to foot shock stress or psychological stress in rats". Psychoneuroendocrinology, 34(2): 226-237, 2009.
Archana, R.; Namasivayam, A.; "The effect of acute noise stress on neutrophil functions". Ind. J. Physiol. Pharmacol., 43(4), 1999.
Dhabhar F.S.; "Stress-induced augmentation of immune function—the role of stress hormones, leukocyte trafficking, and cytokines". Brain, Behav. Immun., 16(6): 785-798, 2002.
Dhabhar F.S.; "Bidirectional effects of stress and glucocorticoid hormones on immune function: possible explanations for paradoxical observations". Psychoneuroimmunology, 2001.
Segerstrom, S.C.; Miller, G.E.; "Psychological stress and the human immune system: a meta-analytic study of 30 years of inquiry". Psychological Bulletin, 130(4): 601, 2004.
Marino, F.; Cosentino, M.; "Adrenergic modulation of immune cells: an update". Amino Acids, 45(1): 55-71, 2013.
Scanzano, A.; Cosentino, M.; "Adrenergic regulation of innate immunity: a review”. Front. Pharma., 6:171, 2015.
Downloads
Published
Issue
Section
License
Copyright (c) 2024 Zainab A. A. Al-Shammary, Sally A.K., Zainab Sameer Sabti, Jamela Jouda, Sabah A. Hameid
This work is licensed under a Creative Commons Attribution 4.0 International License.
.jpg)
