الفعالية التثبيطية لمقرنفل (cloves )في نمو البكتريا aeruginosa Pseudomonas داخل وخارج الجسم

Abstract

Abstract:

This study tested the inhibition activity of the cloves extract on the P.aeruginosa growth and the bacteria was sensitive to the extract with concentration 20% and percentage of the inhibition increase with the increased of concentration also the study included MIC value determination and the minimal inhibition concentration of bacteria growth was 16 mg/ml and LD50 value in vivo was determinated according to MIC value and it was about 2000 mg/kg. The results justified the ability of extract to confer a protection for the Lab animal when given for seven days by its ability to keep the hematological parameters within the acceptable physiological limits on the histology of liver and kidney .These parameters of blood and the internal organs were highly affected, with wide deviates from the normal ones, when the animal were treated by P. aeruginosa alone.