Synthesis, X-Ray Crystal Structure, Bactericidal and Kinetic Study of some Mononuclear Zinc and Mercury Complexes Supported by Bisaroylhydrazone Derivatives

  • Refaa Burhan Kazem Department of Chemistry, College of Science, Al-Mustansiriya University, P.O Box 46010, Baghdad-Iraq.
  • Ahmed Jasim M Al-Karawi Department of Chemistry, College of Science, Al-Mustansiriya University, P.O Box 46010, Baghdad-Iraq.
Keywords: Mononuclear complexes, Bisaroylhydrazone, Kinetic studies

Abstract

 This work includes the synthesis of two derivatives of cyclohexane bisaroylhydrazone: (L1) and (L2). These compounds were synthesized via the condensation reaction of 1,2-cyclohexanedione with an appropriate hydrazide derivative in acidic medium. The prepared ligands were reacted with zinc chloride or mercury chloride under ambient conditions. Consequently, mononuclear type complexes: [Zn(L1)Cl2] (1), [Zn(L2)Cl2].CH3CN (2). [Hg(L1)Cl2] (3) and [Hg(L2)Cl2].CH3CN (4) were obtained. Different techniques have been used to characterize the prepared organic ligands and their metal complexes (X-ray single crystal crystallography and microelemental analyses in addition to infrared, nuclear magnetic resonance, X-ray powder diffraction, Ultraviolate-visible-Near infrared, and mass spectroscopes). Depending upon the X-ray crystallography, it seems that the obtained products of 1, 2, 3 and 4 are mononuclear complexes. Each structure comprises a
[M (L)]2+ core. The kinetic of complex formation of 2 was investigated and the results are investigated and compare with that of 4. The study showed in general, the formation of 2 and 4 in one phase with a first-order type reaction. Antibacterial activities of all the prepared compounds against some pathogenic bacteria (Staphylococcus aureus and Escherichia coli) were evaluated, which exhibit a good growth inhibitory activity.  

Published
2019-03-01
How to Cite
Kazem, R. B., & Al-Karawi, A. J. M. (2019). Synthesis, X-Ray Crystal Structure, Bactericidal and Kinetic Study of some Mononuclear Zinc and Mercury Complexes Supported by Bisaroylhydrazone Derivatives. Al-Nahrain Journal of Science, 22(1), 15-24. Retrieved from http://anjs.edu.iq/index.php/anjs/article/view/2089
Section
Articles