SYNTHESIS OF NEW 1,2,3-TRIAZOL-4-YL-6-SUBSTITUTED-S-TRIAZOLO[3,4-B]-1,3,4-THIADIAZOLE DERIVATIVES VIA DIAZONIUM SALTS.

  • Sawsan H Shawkat Department of Chemistry, College of Science, Al-Nahrain University.
  • Nasreen R Jber Department of Chemistry, College of Science, Al-Nahrain University, Baghdad-Iraq.
  • Yehya K Al-Bayati Department of Chemistry, College of Science, University of Baghdad.
Keywords: NON

Abstract

Derivatives of 6-aryl-[5-methyl-1-(4-methoxy phenyl)-1,2,3-triazol-4-yl-s-triazolo[3,4-b]-1,3,4-Thiadiazoles (9) and (10) were synthesized by treating p-anisidine with sodium nitrite followed by the addition of sodium azide. Treating azide compound (3) with ethylacetoacetate yielded 1,2,3-triazolo-4-carboxylic acid (4), which was converted to ester (5) using absolute ethanol. Treating the ester with hydrazine hydrate afforded the acid hydrazide derivative (6), which was reacted with CS2 and KOH to produce the salt potassium dithiocarbazate (7). Addition of hydrazine to the salt produced 1-amino-2-mercapto-5-[5-methyl-1-(4-methoxy phenyl) –1,2,3-triazol-4-yl]-1,3,4-triazole (8). Treating (8) with p-chlorobenzoic acid and anisic acid afforded the target compounds (9) and (10).

Published
2018-08-24
How to Cite
Shawkat, S. H., Jber, N. R., & Al-Bayati, Y. K. (2018). SYNTHESIS OF NEW 1,2,3-TRIAZOL-4-YL-6-SUBSTITUTED-S-TRIAZOLO[3,4-B]-1,3,4-THIADIAZOLE DERIVATIVES VIA DIAZONIUM SALTS. Al-Nahrain Journal of Science, 10(2), 50-53. Retrieved from https://anjs.edu.iq/index.php/anjs/article/view/1430
Issue
Vol 10 No 2 (2007): December
Section
Articles
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